Infusion Rate (mL/h) = (Total Volume to be infused in mL) / (Total Time for Infusion in hours)
Given:
- Doribax dose: 250 mg
- Diluent: 250 mL of NS
- Infusion time: 2 hours
The drug concentration is calculated as follows:
Drug Concentration = Doribax dose / Diluent volume
Drug Concentration = 250 mg / 250 mL
Drug Concentration = 1 mg/mL
Now that we know the drug concentration, we can calculate the total volume of the Doribax solution as follows:
Total Volume = Doribax dose / Drug Concentration
Total Volume = 250 mg / 1 mg/mL
Total Volume = 250 mL
Next, we can calculate the infusion rate using the formula:
Infusion Rate = Total Volume / Infusion Time
Infusion Rate = 250 mL / 2 hours
Infusion Rate = 125 mL/h
Therefore, the Doribax should be infused at a rate of 125 mL per hour using an IV controller in this scenario.

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